Advanced Biomedical Research

CASE REPORT
Year
: 2020  |  Volume : 9  |  Issue : 1  |  Page : 65-

Rhabdomyolysis and muscle necrosis induced by lead poisoning


Behnaz Ansari1, Gholamali Dorooshi2, Sahar Sadat Lalehzar2, Abolfazl Taheri3, Rokhsareh Meamar2 
1 Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
3 Health Information Technology Research Center, Clinical Informationist Research Group, Isfahan University of Medical Sciences, Isfahan, Iran

Correspondence Address:
Dr. Rokhsareh Meamar
Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan
Iran

A case is presented on a 40-year-old male with chronic lead poisoning with loss of consciousness, rhabdomyolysis, and acute renal failure after occupational exposure. Physical examination revealed generalized atrophy, tenderness, and swelling in the right limb and a decreased proximal muscle strength in the lower limb. A severe acute polyradiculoneuropathy in lower limbs documented by electromyography. All paraclinical tests were normal except increased blood lead level (75 μg/dl) and blue line in gum of the teeth. The patient was treated with penicillamine (500 mg q8 h) and pyridoxine (50 mg daily) for 8 months, only accessible drug in Iran. Force of patient's muscles in the proximal part of the lower limb was improved, and also the blood lead level reached to normal range. This is the first patient with rhabdomyolysis and muscle necrosis induced by lead poisoning.


How to cite this article:
Ansari B, Dorooshi G, Lalehzar SS, Taheri A, Meamar R. Rhabdomyolysis and muscle necrosis induced by lead poisoning.Adv Biomed Res 2020;9:65-65


How to cite this URL:
Ansari B, Dorooshi G, Lalehzar SS, Taheri A, Meamar R. Rhabdomyolysis and muscle necrosis induced by lead poisoning. Adv Biomed Res [serial online] 2020 [cited 2020 Dec 1 ];9:65-65
Available from: https://www.advbiores.net/article.asp?issn=2277-9175;year=2020;volume=9;issue=1;spage=65;epage=65;aulast=Ansari;type=0