REVIEW ARTICLE |
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Year : 2014 | Volume
: 3
| Issue : 1 | Page : 138 |
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Platelet-rich plasma application in chondrogenesis
Azadeh Kabiri1, Ebrahim Esfandiari2, Abolghasem Esmaeili3, Batool Hashemibeni2, Abbas Pourazar4, Mohammad Mardani2
1 Department of Anatomical Sciences, Paramedical School, Guilan University of Medical Sciences, Langeroud, Iran 2 Department of Anatomical Sciences and Molecular Biology, Isfahan University of Medical Sciences, Isfahan, Iran 3 Department of Biology, Molecular and Developmental Division, Faculty of Sciences, University of Isfahan, Isfahan, Iran 4 Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Correspondence Address:
Mohammad Mardani Department of Anatomical Sciences and Molecular Biology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan Iran
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2277-9175.135156
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Platelet-rich plasma (PRP), an autologous derivative of whole blood, has been recently used in surgical treatment. PRP contains growth factors including transforming growth factor-β (TGF-β), insulin-like growth factor (IGF), platelet-derived growth factor (PDGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF) and also bioactive proteins that influence the healing of tendon, ligament, muscle, and bone. This article describes the current clinical applications of PRP in chondrogenesis. This study reviews and evaluates the studies that have been published in the field of chondrogenesis. All aspects of using PRP in chondrogenesis are reviewed. |
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