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RESEARCH ARTICLE
Year : 2016  |  Volume : 5  |  Issue : 1  |  Page : 99

Adverse effects of BCG vaccine 1173 P2 in Iran: A meta-analysis


1 Department of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran
2 Department of BCG, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran
3 Department of Cellular and Molecular Biology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran
4 Department of Bacteriology, Medical School, Tarbiat Modarres University, Tehran, Iran
5 Technical Office, Pasteur Institute of Iran, Tehran, Iran
6 Isfahan University of Medical Sciences, Isfahan, Iran

Correspondence Address:
Dr. Hossein Khanahmad
Department of Molecular Biology, Pasteur Institute of Iran, Isfahan
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2277-9175.183659

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Although in the last two decades the World Health Organization (WHO) has introduced tuberculosis as “a threat to global”, the vaccination with the Mycobacterium bovis Bacillus Calmette-Guerin (BCG) is the only way for the prevention of this fatal infectious disease. Despite of the efficacy of BCG vaccine especially against infants' meningitis, it has still some limitations due to a variety of adverse effects. Many studies have evaluated the side effects of different strains of BCG vaccines in different countries. In Iran, some studies have been done so far to evaluate the adverse effects of 1173 P2 strain which is used for BCG vaccination. Each of these studies have used different standardization and sampling methods. This review will survey all studies that have been published about adverse effects of 1173 P2 strain of BCG vaccine in Iran using data mining methods.


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